Sentence examples for be explained by receptor from inspiring English sources
This cannot be explained by receptor binding or internalisation behaviour which was comparable for both compounds, therefore probably related to the differences in pharmacokinetics by introducing another bifunctional chelator.
Lower recruitment by the monomer at the 10 µg dose compared to the 1 µg dose also cannot be explained by receptor binding affinity (Figure 1).
Different tissue-specific effects may be explained by receptor expression patterns, receptor densities, or even different receptor types.
This could be explained by receptor resistance, as previously described for HepG2, Daudi and Raji lymphoma cells.
These rough comparisons indicate that the effect seen for the histological malignancy grade probably is to be explained by receptor status.
This finding cannot be explained by receptor specificity of pandemic (H1N1) 2009 virus because Childs et al. (14 ) showed that representative pandemic (H1N1) 2009 viruses bound not only to most α2 6-linked sialyl moieties, irrespective of the backbone chain length and type, but also to a considerable range of α2 6-linked sialyl residues.
Homologous desensitization of NPY signalling might be explained by receptor-G protein uncoupling, while heterologous desensitization by BK could be the result of either transient depletion or inhibition of a mediator in the calcium signalling cascades activated by NPY.
Third, the biphasic effect of norepinephrine may be explained by its receptor affinity.
The extraordinary wide range of GC actions can be explained by GC receptor presence in three cell compartments: nucleus, cytoplasm, and plasma membrane.
The relation between beta-blockers and diabetes can be explained by β2 receptor blockade, induced reduction in thermogenesis and subsequent weight gain [ 90- 92].
These findings may be explained by differential receptor coupling to multiple Gα subunits or by the potential for agonist and antagonist 5-HT6 ligands to act on distinct neuronal populations.
