Some new variants persisted for a long period of time at a low level which could be explained by ongoing mutations that allowed partial but incomplete evasion of the host immune response but did not result in increased virulence or circulation in a totally immunologically naïve population that would result in activity levels of epidemic proportion.
Such a delay in presentation may be explained by ongoing immunosuppressive therapy.
In addition, we observed a decreasing proportion of IDUs among HIV-infected women giving birth, which might be explained by ongoing heterosexual transmission of HIV from HIV-infected male IDUs and some heterosexual transmission outside of the traditional high-risk groups.
Out of the 57 neurons analyzed, three neurons had significantly more action potentials after the stimulus than could be explained by their ongoing firing rate before the thalamic stimulus across all binning sizes (Figure S4; p<0.05).
We suggest that timing of eviction by the naked and blind cuckoo chick can be explained by an ongoing coevolutionary arms race between hosts and parasites [45], whereby hosts escalate to evolve increasingly specialized responses to reduce the cost of parasite adaptations to circumvent rejection [46].
Interestingly, in a recent review, Fallon [ 18] proposed that the persistent symptoms might be explained by an ongoing cytokine response, without infection, in the central nervous system (CNS).
A correlation between presepsin and inflammatory biomarkers, such as CRP, WBC, IL-6 and PCT, can be explained by the ongoing systemic activation of inflammatory biomarkers during severe sepsis and septic shock [ 3, 24].
This latter observation could be explained by an attempt at ongoing endothelial repair/remodelling in patients with active subclinical vasculitis, as suggested by our previous studies of systemic vasculitis in children.
This difference may be explained by the lower risk of ongoing transmission within the community in high-income countries and also the greater likelihood that contacts will have been treated for LTBI in high-income countries [ 109, 186, 235].
The longer high levels of unemployment stretch on, the less they can be explained by weak demand.And then there is the ongoing debate within the Federal Reserve between inflation hawks and those fearing deflation.
This pattern in findings, which details changes in cognitive scores may be explained by two major facets: (i) children's ongoing enactive learning experiences, as discussed in the preceding section, and (ii) the ease of 'memorization'memorization
