Sentence examples for be explained by mutations from inspiring English sources
Resistance to rifampicin (RIF) can be explained by mutations in rpoB (beta-subunit of RNA polymerase).
The absence of miR-137 in 501mel cells might be explained by mutations in the miR-137 gene itself as has been shown to be the case in other melanoma cells [31], thus allowing high levels of MITF expression.
On the contrary, it has been argued that mutator mutations (MM) are unnecessary for cancer development, and that the observed incidence rates of cancer may be explained by mutations occurring at the normal rate in conjunction with multiple rounds of lineage expansion and selection [11] [14].
The majority of changes can be explained by mutations in splice sites.
The ofloxacin resistance of isolates X122 and X189 can be explained by mutations in D94 in gyrA.
This difference can be explained by mutations in transcriptional regulators such as BCG3734 (crp) and BCG0484c (sigK) in late BCGs.
The alternative view, applicable to characters other than body size or wing length, is that patterns of evolutionary change can either be enabled or directed by the mutational process itself and thus properly be explained by mutation rather than natural selection.
If the frequency of two or more discontinuous forms within a species is too high to be explained by mutation, the variation as well as the population displaying it is said to be polymorphic.
As the divergence between D. melanogaster and D. simulans does not follow this pattern, the drop in variability cannot be explained by mutation rate variation, but is attributed to selection [27], [28].
Thus, cancer incidence patterns across lifespans cannot be explained by mutation accumulation alone, regardless of the type of cancer or organism studied.
