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Major features can be explained by modification of the amplitude of the diurnal cycle through SST variations, as mentioned in the first subsection.
Whereas hypermethylation of CpG islands occurs frequently in HNSCC, S100A8/A9-dependent regulation of MMP-2 could not be explained by modification of the upstream promoters of MMP2 or TIMP2.
Findings of previous studies and the present data suggest that migraine prophylaxis with different centrally acting substances may be more complex and cannot only be explained by modification of cortical excitability.
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So, the lack of correlation between cardiac output and Pvc-aCO2 found in septic patients [6] should be explained by modifications in the dissociation of CO2 from Hb. Disorders such as hemodilution and lactic acidosis are commonly present in septic shock and frequently display microvascular abnormalities.
Our findings can also not be explained by modifications of adhesion and growth factor associated signaling involving FAK, Paxillin, p130CAS, AKT1 and MAPK under suspension and serum withdrawal relative to adhesion plus serum conditions.
This could in part be explained by modifications of blood flow distribution and oxygen extraction by brain and splanchnic tissue.
The simultaneous degeneration of stamens and the conversion of petals to sepals in the 'bud-flowering' type cannot be explained by modifications of the 'ABCDE'-model.
Several studies have highlighted that differences in omega-3 PUFA levels in blood samples of pregnant women cannot be explained by modifications in dietary intake alone [ 24, 25].
This could be explained by modifications in tumor cell gene expression induced by the first treatment, which may have influenced the subsequent response of tumor cells to docetaxel + trastuzumab.
The latter results have reported changes in the traditional gender differences of coping with LEs, might be explained by modifications in social resources, and gender role expectations [ 2, 24- 26].
This effect can probably be explained by modifications of the expression of cell-cycle-related proteins (ongoing research), as described for other cytokine such as interferon γ (Matsuoka et al, 1999; Gooch et al, 2000), and by the fact that TNF α induces BxPC-3 cycle distribution modification which may render the cells more radiosensitive.
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