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80.4 to 91.5% of these were found to have correlated genotypes across the RI strains (i.e., Strain Distribution Patterns (SDPs)), most of which (>67.9% (Table S1)) could be explained by linkage disequilibrium (LD) (Figure 1).
Deviations from HWE can be explained by linkage disequilibrium (LD) or the occurrence of null alleles.
The differences between CCR2 polymorphism investigations in sarcoidosis may be explained by linkage disequilibrium between CCR2 gene variants and polymorphisms in a neighboring sarcoidosis susceptibility gene.
This may be explained by linkage disequilibrium between the associated variant and a true functional variant, or by a regulatory effect of a non-coding variant.
The fact that this LD generated by family structure can be explained by linkage analysis (LA) implies that GS can also use LA information.
Thus, the observed association between skewed XCI and AITD and RA is not causal but could be explained by linkage disequilibrium between mutation responsible for XCI process and AITD and RA susceptibility polymorphisms.
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This LD allows close genetic relationships between animals within the pedigree, which are explained by linkage analysis (LA).
This phenomenon can be explained by the linkage of deleterious, beneficial, and neutral mutations within haplotypes and selecting them as whole units.
It has been hypothesized that the association of the rs780094 GCKR polymorphism with hepatic fat accumulation can be explained by the linkage disequilibrium with rs1260326, encoding for the P446L protein variant.
Part of the genetic susceptibility of the disease could also be explained by demonstrated linkage or association of familial psoriasis to a locus on 17q25 (PSORS2) [ 4, 14, 26].
The detection of QTL for multiple traits on the same linkage groups (e.g. Chr 4) can be explained by either the linkage of two QTL (one for each trait), or the presence of a single QTL with pleiotropic effects.
More suggestions(15)
be defined by linkage
be found by linkage
be explained by variant
be explained by demand
be explained by tolerance
be detectable by linkage
be summarized by linkage
be explained by reselling
be guaranteed by linkage
be affected by linkage
be explained by travel
be caused by linkage
be captured by linkage
be performed by linkage
be confounded by linkage
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