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Downregulation of a genomic region could be explained by induction of changes in the chromatin structure through e.g. DNA methylation and/or histone modifications.
In studies on infliximab, an effective biological treatment for RA which blocks TNFα [22], a marked decrease in synovial macrophage numbers occurred already 24 hours after initiation of treatment, which could not be explained by induction of apoptosis [8] [11].
The activities of either GSTs or EHs expressed in vivo exhibit a relatively large interindividual variation, which might be explained by induction, inhibition, or genetic factors.
A strong signal was obtained after wounding which could be explained by induction of the acidic chitinase itself or of an isoform.
These results suggest that the growth inhibition observed with LY2784544 treatment could be explained by induction of the apoptotic pathway through the inhibition of the JAK2V617F-STAT5 pathway in the mutant JAK2-expressing cells.
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The decreased exchange was explained by induction of a DNA damage response and consequent induction of PARP, for which the coenzyme NAD+ is a substrate (Day et al, 2007; Witney et al, 2009).
The effect of coxibs on the biology of the tumour has been explained by induction of apoptosis, inhibition of angiogenesis and by a decreased invasive potential of tumour cells [ 7].
This induction might be explained by the induction of the chemokine signaling, as identified by the KEGG software.
These results support the view that the rapid decrease in synovial cellularity observed after initiation of anti-TNF therapy cannot be explained by apoptosis induction at the site of inflammation [ 31].
In the vaccinated chickens, the titers of neutralization antibody reached 7 9 values, showing that protection could be explained by the induction of a sufficient humoral response.
This situation could be explained by the induction of plant defense by plant cell wall-interacting proteins, which could be detrimental to the biotrophic lifestyle.
More suggestions(15)
be derived by induction
be explained by demand
be caused by induction
be explained by tolerance
be intensified by induction
be established by induction
be verified by induction
be explained by reselling
be explained by travel
be readout by induction
be defined by induction
be activated by induction
be explained by hurt
be given by induction
be explained by brain
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