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The observed plasticity of Th17 cells towards the Th1 phenotype can be explained by extensive epigenetic priming of the IFNG locus in Th17 cells.
As mentioned above, we believe the long standing and hitherto unexplained complexity of the dumpy gene can best be explained by extensive alternative splicing where dpolv nonsense mutations tag constitutive exons presumably located at several different places in the gene.
Although the presence of these proteins could be explained by extensive sequence divergence, the possibility that they may have originated independently cannot be excluded.
The smaller influence of medical specialists for rosuvastatin, esomeprazole, and rofecoxib may partly be explained by extensive marketing and the relative low perceived risk associated with prescribing of these drugs [ 22- 24].
This mutuality can be explained by extensive lateral gene transfer between these organisms, as they evolve to thrive in the same types of environments (high temperature and low pH).
Theoretically, this observation can be explained by extensive looping of the DNA in this region, which in turn would allow the tethered DNA methyltransferase to reach more distant regions of the DNA sequence.
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The experimental results are explained by extensive calculations of the polarized local fields at the fundamental and second-harmonic frequencies.
The poor outcome after MI in patients with DM has been explained by extensive atherosclerotic lesions, increased myocardial susceptibility to ischemia/reperfusion injury, and contractile dysfunction of the myocardium, often called "diabetic cardiomyopathy" [ 3].
The disparity in casualties can only be explained by the extensive use of US airpower.
This difference might be explained by more extensive preoperative positioning in the robot group.
It must rather be explained by an extensive washover event which inundated at least the western part of the Lefkada Lagoon.
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