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This could possibly be explained by disruption of a positive feedback-loop in which Notch signalling upregulates Notch mRNA expression.
This higher susceptibility of the mutant strain might be explained by disruption of the TruMDR2 gene.
The disorderly emergence of organ primordia in fil-9 plants can be explained by disruption of these boundary domains.
The effect of the chaperones can be explained by disruption of the strong secondary and tertiary structure of the target RNA by the selective hybridization of helper molecules.
Overall, the structure of the V266H variant demonstrated that the inhibition could not be explained by disruption of the short-range allosteric network because the His His266′ side chains were accommodated in the interface, albeit with repositioning of neighbouring tyrosine side chains.
Compared with single nucleotide polymorphisms (SNPs), CNVs seem to have a stronger impact on phenotype and are shown to have effects on changes in gene expression levels [ 6], which can be explained by disruption of gene dosage, unmasking of recessive alleles, and loss of regulatory elements or regulatory polymorphisms [ 7, 8].
Similar(51)
The patient's neurological findings can be explained by disruptions of the corticospinal tract, corticobulbar tract and paramedian pontine reticular formation.
This may be explained by the disruption of social ties as they finish school, but also because work environments offer less meaningful social interactions for young workers.
Nevertheless, the cancer-associated genome hypomethylation could be explained by the disruption of interactions existing between Dnmts and the DNA replication and DNA repair proteins because these interactions play a crucial role in the DNA methylation in mammalian cells [6], [7], [8].
Both of these phenotypes could be explained by the disruption of REs.
These results can be explained by a disruption of the heterotrimer with a concomitant generation of free βγ dimers.
More suggestions(15)
be published by disruption
be abolished by disruption
be explained by variant
be explained by demand
be explained by tolerance
be mediated by disruption
be explained by reselling
be caused by disruption
be frustrated by disruption
be affected by disruption
be explained by path-dependence
be reversed by disruption
be obtained by disruption
be explained by redirection
be driven by disruption
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