The methodology is explained by demonstrating its advantages against multi-objective optimization approaches.
The utility of the developed platform is explained by demonstrating implementation with material handling system and spindle system, separately.
The majority of these altered genes were upregulated, which may be explained by the demonstrated increase in mitochondrial mass.
The reduction in tubular apoptosis in TLR2−/− mice can also be explained by studies demonstrating a proapoptotic function of TLR2 [48], [48].
The bactericidal effect of HCO3− could be explained by its presently demonstrated ability to induce an increase in cAMP in the bacteria since activation of cAMP has been reported to suppresse protein synthesis in bacteria [48].
Since genetic mobile elements are inactive in the most of N. crassa genome, the detected size variation of SSRs cannot be explained by transposable elements as demonstrated in other systems.
The maximum age of red cells was not significantly associated with hospital mortality when evaluated as a continuous variable, but had a significant association when evaluated using quartiles, which can be explained by the nonlinear association demonstrated in Figure 1.
Further, the mutants of CIITA, which produced the highest level of Gag-Pol, did not demonstrate a linear increase in Gag processing or virion infectivity, which may be explained by previous work demonstrateing that increased Gag-Pol levels impairs viral infectivity [61], [62].
However, it can be explained by the previous study demonstrating that p21 protects cells from oxidative damage through activation of Nrf2 as an antioxidant response [16], and it was also shown that Bmi-1 is important for NSC proliferation and survival at earlier embryonic stages, via suppression of cell cycle inhibitor p21, potentially with stage-related differences [11].
A general lack of correlation between chromosomal CGH and array data has previously been described in other neoplasms, namely in colon cancer (Platzer et al, 2002), and may be explained by the recent observations demonstrating that changes in DNA copy number induce changes in the expression of only a limited number of genes.
