Sentence examples for be expected to downregulate from inspiring English sources
Thus, inhibition of PKR phosphorylation might be expected to downregulate nuclear binding of NF- κB, as it does in skeletal muscle.
The mTOR inhibitors decrease glucose uptake and may be expected to downregulate fluoro-deoxy-glucose positron emission tomography (FDG-PET) uptake.
Since HIF-1 inhibitors would be expected to downregulate expression of glycolytic enzymes and thus inhibit flux through the glycolytic pathway, the obvious way to test the action of such drugs on tumours would be to look for suppression of FDG uptake using PET.
Therefore, they are expected to downregulate the expression of their respective target genes.
The former scenario should lead to the upregulation of PML through activation of mTOR, while the second is expected to downregulate it.
Microbes that use low-yield pathways converting NADH back to NAD, including L. lactis and S. cerevisiae, are expected to downregulate their high-yield pathways at high growth rates.
This soluble 22-kDa fragment was adequate for augmentation of MMP-2 expression in human fibroblasts, while the cleavage of membrane CD147 is expected to downregulate the membrane-specific MMP-activating function of CD147 [ 27].
More remarkable are the lower levels of steroid hormones in immunized birds treated with hormones, since the treatment was expected to continuously elevated hormone levels and downregulate endogenous production by affecting the HPG feedback axis.
Since the data (i.e., Figure 6(b)) was obtained by adding noise to the simulation results after downregulating Rxn44, Rxn44 is expected to be the most likely malfunctioning reaction in this case.
We reasoned that genes activated by Klf5 are expected to show the same expression profile of Klf5, i.e., expressed in undifferentiated ESCs and downregulated when differentiation occurs.
In the presence of Treg, which presumably downregulate functions of other T cells, the level of ζ expression in these T cells is expected to be low, thus providing some indication about activity of Treg.
