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First, the nature of the cell cycle synchronization is not absolute; it is to be expected that cell cycle distribution will vary over the 48 hours of 4OHT treatment, as cell cultures encounter the G1 block imposed by lovastatin or traverse G1 and enter S, in the case of the release from nocodazole.
Neutrophils have been reported to lack delta-6-desaturase and are dependent on incorporation of PUFA from plasma PL (Chilton-Lopez et al, 1996; Barham et al, 2000), therefore, it would be expected that cell and plasma PL PUFA levels would be related.
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According to EMA : "When it is expected that cell-mediated immunity constitutes an important or even essential component of the overall immune response to an antigen, clinical studies to evaluate some type of cell-mediated immune correlates are encouraged".
Because the heptameric PA channel probably uses 7 receptor molecules to internalize at most 3 LF or EF molecules, and the process is unlikely to be error-free, it can be expected that cells on average internalize fewer than 10,000 molecules of LF or EF [25].
Therefore it can be expected that cells at the cluster boundary behave differently compared to cells within the cluster.
If metastatic capacity was due to a series of heritable mutation events, as predicted in the progression theory, it might be expected that cells that had successfully completed the metastatic cascade would be more efficient at establishing new metastatic tumors than the primary tumor.
It is expected that cell membrane damage and biofilm inhibition would have a substantial effect on pathways and genes related to cell wall synthesis and metabolism.
It is expected that cells using 10 cycles of CdTe can yield higher JSC value compared to other cells only due to the increase in thickness of CdTe.
Complete separation is estimated to occur after 80 s of transit through the channel, but it is expected that cells will be sufficiently segregated to collect the populations in separate outlets at an earlier time.
In other words, it is expected that, as long as cells proliferate, void space in the scaffold increases and degradation rate of the material should match growth rate due to healing or regeneration process.
It could be expected that necrotic cell death is the main event with exposure to high levels of Cd.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com