As would be expected in a developmental cohort, the variability of anatomically plausible components tended to be well explained by the combination of age and log-transformed age.
These processes, which include biosynthesis/metabolism, transport, cell growth and organogenesis, gene regulation, photomorphogenesis, response to phytohormones, response to biotic/abiotic stresses, disease resistance, and DNA biogenesis (see Additional files 1 and 3, 4, 5, 6, 7), are clearly congruent with what would be expected in a developmental phenomenon like that examined here.
As would be expected in a high-risk cohort early in the developmental course of illness, the GAF scores were comparable to controls.
Although in some cases, the function studied may be highly conserved and non-variant, often, species variations should be expected, even in conserved developmental processes.
Though mean viability/developmental competence may differ significantly, a small subset of embryos cultured in the sub-optimal medium could be expected to have developmental potential comparable to sub-average embryos from the optimized medium group.
As could be expected from its role in developmental angiogenesis, the Delta-Notch pathway is also important in tumour angiogenesis.
Although mutations in RP genes, like other housekeeping genes, would be expected to result in nonspecific developmental defects with widespread phenotypes, we found that knockdown of some RP genes resulted in phenotypes specific to each gene, with varying degrees of abnormality in the brain, body trunk, eyes, and ears at about 25 hours post fertilization.
Could the authors comment on how such late expression changes would be expected to alter early developmental patterning events in the shark?
After all, that is when the books said that babies can be expected to reach this developmental milestone.
Photorespiratory activity usually increases with advancement in leaf development [ 18, 19], and would be expected to increase during the developmental period in this study.
