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These have all been seen to occur in more cells than would be expected from direct exposure alone (Belakov et al, 2001), and were reduced when cells were incubated with GJIC inhibitors (Azzam et al, 2001).
However, responses in the human MTL, like the ones reported here, have a much later onset (~300 ms) [ 15, 16, 18] than what would be expected from direct feedforward projections from ITC.
This provides a means to assess whether the enhanced sensitivity of cells with activated RAS to the chemotherapeutic drugs described above represents an acute synthetic lethal response, such as might be expected from direct conflict of the cell's response to drug-induced damage with the activated signaling pathways emerging from RAS.
Although we identified up-regulated genes, as it would be expected from direct regulation by ex-siRNAs, the number of down-regulated genes in the mutants was higher than the up-regulated ones, predominantly during the exponential growth, indicating that the loss of function of RNAi components mainly results in repression instead of induction.
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The phenotype of the JBTS patients is different from what would be expected from a direct extrapolation from the animal models.
The CTCF-binding tracks shown in Figure 1C exhibit complexities that may not be expected from such a direct experiment.
We then used Ensembl 60 orthology relationships to determine mouse and rodent-specific genes, and report the relative fraction of such genes for the different binding site categories in Figure S4 D. Related to Figure 1 The CTCF-binding tracks shown in Figure 1 C exhibit complexities that may not be expected from such a direct experiment.
As might be expected from the lack of a direct effect of antibacterial agents on bacterial viability in saliva (Table 4), no contribution of saliva toward the prolonged substantivity of any of the antibacterial agents as delivered during toothbrushing was found (Table 5).
Additionally, lower sensitivity and specificity for detecting headache must be expected from such remote engagements than from making direct contact with everyone in the sample individually.
A signed consent form was used to ensure informed consent and clarify that no direct benefit could be expected from participating in the study.
A consent form was used to ensure informed consent and clarify that no direct benefit could be expected from participating in the study.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com