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As the RDT has been designed with a focus on organic reactions and all algorithms of the RDT rely on substructure matching, incomplete or incorrect mappings can be expected for small molecules.
Fig. 3 shows that linear DNA configurations can only be expected for small DNA length.
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Thus, greater initial cell membrane-NP association would be expected for smaller NP, leading to potentially greater intracellular uptake.
In contrast, the clonal spread of M. pneumoniae can only be expected for small-scale endemic outbreaks with person-to-person transmission in close communities, such as families (37 ).
However, additional resolution gains can be expected for smaller particles with a lower molecular mass, when using exposure-filtered particle sums (see below).
As such, considerable benefits have been expected for small and medium-sized enterprises.
This is expected for small RNAs processed by Argonaute-like proteins (Mi et al. 2008).
However, according to ion hammering mechanism, a large elongation is expected for smaller particles than relatively bigger particles, which contradicts our observation and hence rules out ion hammering effect.
The smaller enthalpy change for 7 is consistent with making fewer interactions with the protein as would be expected for a smaller ligand.
However, a large contribution from facilitated diffusion would not be expected for the relatively small duplexes used in this study.
In contrast, the 20% Col V gel has a smaller measured F/B, which would be expected for a structure comprised of smaller, more randomly distributed fibrils.
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