Regardless of the explanation, caution will have to be exercised in interpreting betatrophin ELISA results by considering which antibodies are used, and which betatrophin species is measured.
Therefore, caution must be exercised when considering TZDs in patients with preexisting cardiac disease.
Caution must be exercised when considering steroid use in severe falciparum malaria, since no benefit has been shown, whereas there are potential adverse effects, such as in the present case where it may contribute to immunosuppression facilitating fungal infection.
Also, as with all animal studies, an element of caution should be exercised when considering knockout mouse results in relation to the situation in humans.
This study emphasises the tumour microenvironment as the critical determinant of successful anti-metastatic therapy, heeding that extreme caution be exercised when considering anti-CCL2 treatment in metastatic disease.
While data in support of this are still emerging [ 42- 44], significant caution should be exercised when considering ILE administration early in the course of life-threatening enteric overdose and steps should be taken prior to use of ILE to ensure absorption is minimised.
Moreover, caution must be exercised when considering the use of adjuvants in a mucosal context, since mucosal application of an adjuvant-containing formulation may induce local inflammation, potentially increasing the HIV-1 transmission risk by recruitment of activated CD4+ T cells that are the primary targets for HIV-1 replication in vivo [9], [10], [11].
Because patients with internal malignancies and melanoma were excluded from the trials, caution should be exercised when considering the use of efalizumab in patients at high risk for malignancy or with a history of malignancy.
For the people who accompany him, the trips are exercises in relational aesthetics, which considers social interaction and experience to be a form of art.
