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Secondly, the loss of affinity upon a mutation could mean that a particular residue is involved in interactions with the ligand in the final binding pose, but it cannot be excluded that such a residue only takes part in the process of ligand entrance or induced-fit.
To conclude, we hypothesize that the imbalance in the miRNA network in the GK rat islets may contribute to the impaired GSIS characteristic of the animals, though it cannot be excluded that such perturbation may serve as a resetting/compensatory mechanism to counteract the disease phenotype.
It cannot be excluded that such physical and/or chemical changes may have affected the properties of L. intracellularis.
Thus, it cannot be excluded that such structures could serve as substrate for Drosha and/or Dicer.
It cannot be excluded that such drugs unspecifically impair memory formation by mechanisms other than DNA-methylation.
Given that connective tissue is a major component of normal breast tissue, it cannot be excluded that such phenomena may be observed systemically.
Similar(49)
Even if the primary agent studied here was fungal cell mass, it cannot be excluded that agents such as cooking fuels or environmental tobacco smoke might influence the exposure outcome and hence the risk of disease.
However, it cannot be excluded that the products contain such substances without listing them on the labels: In 2000, Rastogi found that the declarations of preservatives in the ingredient lists in 45%% of the analyzed skin creams were wrong [31].
Furthermore, it cannot be excluded that other MAPK isoforms such as ERK5, ERK7, p38γ and p38δ are regulated by TNF-α as well in the RA FLS used [ 29].
However, it cannot be excluded that other possible confounding factors such as attraction, emotional valence, preference and interest might have contributed to determine a greater amplitude of LP to dynamic vs. static pictures, or to induce specific sex differences.
Although efforts were made to exclude dogs with respiratory, inflammatory, immune-mediated, neoplastic or infectious diseases, the possibility cannot be excluded that these dogs might develop such disease later in life.
More suggestions(15)
be surprised that such
be excluded that other
be excluded that subcortical
be shown that such
be concerned that such
be expected that such
be excluded that close
be excluded that experimental
be excluded that future
be made that such
be excluded that low
be reassured that such
be satisfied that such
be assumed that such
be told that such
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com