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‡The noninferiority margin Δ is the absolute risk increase in the placebo arm to be exclude with the trial.
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Similarly, it could be excluded with the same certainty in 49 (39%) of the 125 patients of the validation group.
Syphilis is one of the great masqueraders, a disease with such varying symptoms that it can almost never be excluded with certainty.
If, like me, you could never impose the death penalty, you must say so, and you will be excluded, with the grim consequences you describe.
Gastroesophageal reflux is a common cause of atypical chest pain and should be excluded with either appropriate investigation or an empiric trial of proton pump inhibitor therapy.
However, chronic effects can presently not be excluded with certainty, as relevant toxicological data do not exist in the open scientific literature.
Thus, even a modest increase in risk associated with antidepressant use can be excluded with these data.
On the basis of this mpMRI, a clinically significant PC could be excluded with high certainty.
Therefore, we conclude that a subclinical infection cannot be excluded with the adoption of these techniques.
Contamination with maternal blood cannot be excluded with certainty based on the analysis of IgA in cord blood.
In addition, activation via TLR4-MD-2 independent intestinal innate immune receptors cannot be excluded with these experiments.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com