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The host cell's ability to respond to these diverse signals is clearly important, yet may not be evident when using immortalized cell lines due to the various mutations or altered signaling pathways involved in the immortalization process.
Other studies have demonstrated improved persistence with fixed-dose antihypertensive combination regimens as compared to free combinations [ 26]; therefore, some of the persistence advantages found in our study of fixed-dose combinations may not be evident when using free combination regimens.
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However, an effect of salinity was evident when using high-activity clays mixed with fresh water.
Because of the small size of the STN and its variable anatomical location, we repeated our analyses using individually defined ROIs drawn on high-resolution structural scans (see Methods); the same result was evident when using this approach (positive effect of condition t=1.95, P=0.035 main effect of task, P>0.3).
Conversely, no signal was evident when using healthy brain homogenates (columns 4, 8, 12 and 14), or cells incompetent for prion propagation (i.e. the N2a cell line) (Fig. 2, lower panels).
However, for the beef cattle data, no significant QTL were found with LDLA but significant QTL were evident when using EMMA and BayesC.
We were interested whether the same results were evident when using a coarser spatial scale - plot densities instead of NNDs, as another proxy of competition.
There were no clear associations between the GRS13 and all-cause mortality; however, significant associations with CVD mortality and CAC were evident when using the weighted GRS13 (Table 2).
For HG data, a balanced design was evident when using the post-warm-up data for the NOF trial and the post-arm fatigue test data for the ARF trial as the preexercise data.
This was evident when using the large ABCA4 and MYO7A but not the small EGFP transgene, suggesting an advantage of including the AK sequence for large transgene reconstitution in cells like PR which are more difficult to target by AAV2/8 than RPE.
Nevertheless, synergy between CpG and IL-15 was evident when used to stimulate T. cruzi-specific CD8+ T cells in the absence of antigen.
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