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The following evaluable patient populations are defined for selected endpoints: Tumor response will be evaluated in randomized patients with measurable disease at baseline, CA 19 9 response will be evaluated in randomized patients with available CA 19 9 assessment at baseline.
Effects on Kessler-6 were more beneficial for girls least likely to move compared with girls most likely to move (-0.62 vs. 0.02; interaction; P = 0.03).Evidence of individualized treatment selection differed by child gender and outcome and should be evaluated in randomized trial reports, especially when heterogeneous treatment effects are likely and nonadherence is common.
Moreover, non invasive ventilation the current first line therapy of OHS should now be evaluated, in randomized controlled trials, not only regarding its effects on PaCO2, sleep and quality of life but also for its cardiovascular and metabolic impact.
Switching to natalizumab or immunosuppressants in patients with breakthrough disease is effective in reducing clinical activity of relapsing MS. The magnitude of the effect and the risk-benefit ratio should be evaluated in randomized clinical trials and prospective cohort studies.
Ideally, the effect of vitamin A supplements should be evaluated in randomized trials.
Tumor response will be evaluated in randomized patients with measurable disease at baseline, CA 19 9 response will be evaluated in randomized patients with available CA 19 9 assessment at baseline.
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The high-dose tigecycline regimen that Cunha proposes for multidrug-resistant organisms has never, to our knowledge, been evaluated in randomized trials or even in large prospective evaluations.
Lung cancer screening with low dose computed tomography (CT) has not yet been evaluated in randomized clinical trials, although several are underway.
Surprisingly few antibiotic schedules prescribed for the treatment of CLD have been evaluated in randomized double-blind placebo-controlled clinical trials (RCTs).
The frequency of reporting of 11 basic elements of design and analysis was evaluated in randomized clinical trials (RCT), nonrandomized clinical trials (NRCT), and retrospective cohorts (RC) from JPS by consensus of 2 assessors.
2,4-D, Puma super, 2,4-D + Puma super at 1.25 L ha−1 each, Affinity at 2 kg ha−1 and weedy check were evaluated in randomized complete block design with split plot arrangement replicated four times.
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