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TPE worth to be evaluated in large trials in ACLF' patients, with a liver transplant project, and a lesser degree of organ failure.
Ideally, the LLDI should be evaluated in large, population-based samples.
Ultimately, the efficacy of IKK 16 and similar molecules needs to be evaluated in large mammals before moving to Phase 1 safety studies in humans.
Although promising, such polymorphisms of the TCR gene have yet to be evaluated in large, prospective studies or by genetic analysis of familial IgAN [ 24].
This will entail the future development of practical methods for the inhibition of fibrinogen that will be evaluated in large scale studies.
The role of the TCI in assessing quality of care, in the UK NHS at least, should be evaluated in large study of large teams.
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Although these agents may represent appropriate first-line therapies for men with OAB symptoms, the therapeutic potential of antimuscarinics alone or in combination with α1-receptor antagonists in this population should be evaluated in large-scale, well-designed clinical trials.
Similarly, within the drug discovery pipeline ChEBI has been used as one of several systems within which chemicals can be classified or grouped in order for patterns to be evaluated in large-scale high-throughput data [26].
The impact of morbi-mortality of RV systolic dysfunction screening in ARDS has to be evaluated in larger cohorts.
"It looks as strong if not stronger than any other markers I've seen," he says, although he cautions that prognostic markers like this must be evaluated in larger studies.
Prenatal ultrasound remains the standard diagnostic method, but fetal MRI seems to be an excellent complementary imaging technique, and its real utility should be evaluated in larger, multicentric series.
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