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In addition, to ensure reproducibility between different laboratories, it is important that clinically used assays be evaluated in external quality assessment (EQA) programs [ 38].
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First, the prognostic potential of aberrant biomarker gene expression was evaluated in external microarray and RNASeq datasets (Cohorts I-II).
Furthermore, reestimation of regression coefficients for existing models may result in better performance when models are evaluated in external populations (71).
Because metric proximity is relative (i.e. it refers to a spatial continuum) and can only be evaluated in relation to some external reference framework, it makes sense to talk about groups of groups in the same way as about groups of clusters.
In addition, the prediction needs to be evaluated in an independent dataset (external validation) to demonstrate its value.
These descriptors should then be evaluated in an unbiased manner and preferably using an external dataset [10].
During ERCC Testing, candidate external RNA controls will be evaluated in both microarray and QRT-PCR gene expression platforms.
Multivariate prediction models need to be evaluated in cohorts distinct from the derivation set to determine external validity.
Its predictive properties were evaluated in an external data set of children 0 18 years old, including comparison of dose prediction accuracy with three pharmacogenetics-based algorithms for children.
Secondly, the risk-prediction model, PUMCH model, has not been evaluated in an external large cohort and those deemed low-risk women were not followed up in the study, which made it impossible to verifying the model.
The outdoor thermal environment is evaluated in terms of external surface temperature and mean radiant temperature (MRT).
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