In the coupled method, both the external dynamics and the internal mechanics are evaluated directly by numerical simulations that follow the model of Pill and Tabri (2011).
The rate of ribosome biogenesis was evaluated directly by measuring the level of incorporation of 3H-uridine within cytoplasmic ribosomes of MP and MA- cells.
In these studies, mutations were generated by error-prone PCR and average base substitution rates from libraries of clones were evaluated directly by sequencing.
This possibility was evaluated directly by examining the effect of shRNA-mediated knockdown of NRP1 and NRP2 on the migratory response of primary cultures of rat arterial SMC (RAoSMC) to PDGF-BB.
All patients were evaluated directly by one of the co-authors with specialty training in neurology, child neurology and/or clinical genetics, and in accordance with local medical practices.
The construct validity is examined by convergent and discriminant validities with related constructs, here with the personality dimensions according Cloninger's biopsychosocial model, and the construct validity, in terms of diagnostic validity, is evaluated directly by comparing the AIDA scores on scale and subscale level between psychiatric patients and healthy controls.
Instead of formulating and rejecting non-meaningful null hypotheses, the Bayesian approach is used to investigate differences in effect sizes which can be evaluated directly and intuitively between all groups, by comparing posterior (i.e. estimated from the model) means and credible intervals.
Rather, the results of parametric tests should be evaluated directly.
Generally, the most significant property of the collocation method is its fluency in the application; e.g., matrix elements of the given equation are evaluated directly rather than by numerical integration as in the Galerkin procedure.
