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PreP needs to be evaluated alone and in combination with other approaches such as universal testing and early treatment of HIV infections to determine the best means to decrease the incidence of HIV infections worldwide.
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To simulate the conditions of use, MPS were evaluated alone and in combination with contact lenses.
The antitumour efficacy of lipid A mutant Salmonella was evaluated alone and in combination with X-rays in mice bearing B16F10 or Cloudman S91 melanomas.
Bishop score (≥4), fetal fibronectin level (≥50 ng/mL), and cervical length (≤25 mm) at 24 weeks' gestation were evaluated alone and in sequence as tests to predict spontaneous delivery before 35 weeks' gestation.
Analysis of cytometry data was done with FlowJo software (Tree Star, Ashland, OR); for experiments measuring five functional responses, individual cytokine gates were evaluated alone and also processed through Boolean combinations to partition responding cells into one of 31 possible specific response categories.
Model performance was evaluated alone, and in combination with simple disease-specific models.
The safety and immunogenicity of a new candidate tuberculosis (TB) vaccine, FP85A was evaluated alone and in heterologous prime-boost regimes with another candidate TB vaccine, MVA85A.
The effect of lovastatin on ovarian cancer cell lines was evaluated alone and in combination with cisplatin and doxorubicin using several assays (MTT, TUNEL, fixed PI, PARP cleavage) and synergy determined by evaluating the combination index.
Enzastaurin was evaluated alone and in combination with the EGFR inhibitor gefitinib, on growth and signalling protein expression in human cancer cells sensitive and resistant to anti-EGFR drugs, both in vitro and in nude mice.
Since the embedding capacity and embedding distortion cannot be evaluated alone without taking each other into account, a reasonable way of evaluating them would be to fix one of the two factors and see how the algorithm performs in terms of the other factor.
This is extremely important because even though a soluble non-protein component of a biological sample could be evaluated alone, the influence of a protein antioxidant reserve as a part of a whole should be decisive and must be taken into account.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com