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The solution to the optimum input design problem depends on the unknown parameters to be estimated which is often approximated by an initial estimate.
In this example, noise variances θ 2 and θ 3 are unknown and must be estimated, which is not a typical task.
First, the position of the transcription start site (extremity of the 5′UTR region) can be estimated, which is helpful for specifying sRNA interaction regions onto mRNA transcripts.
From these concentrations a dissociation constant of 5 nmol L−1 can be estimated, which is the dissociation constant of a high-affinity binder.
19 The Cox regression and recent modern survival techniques, in contrast, permit effects of risk factors (determinants) to be estimated, which is critical for designing interventions.
For the 2009 world championships in athletics, 12 an illness incidence of 7.6 per 1000 athlete days could be estimated, which is similar to that in the present study.
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From these measurements, the nanotube bandgap energy could also be estimated, which was quite comparable to that determined by spectroscopic measurements.
To implement the VAD scheme, the variance of the noise MP coefficients requires to be estimated, which are assumed to be known in Equation (14).
That is, the fine-resolution pixel coefficients to be estimated, which are expressed as vectors w ~ j in (14), are modeled to be independent for different index j.
That was, if the iron/sulfur concentration, pH value, temperature and microorganism had been obtained in a natural bioleaching system/mine, the potential metal recovery efficiency might be estimated, which was significative for mine selection in industry applications.
Using these and other pharmacokinetic data, such as hepatic clearance (CLH), bioavailability and in vitro t1/2 can be estimated which are very important to aid in defining relationships between in vitro and in vivo correlation behavior.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com