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The QALY value will be estimated using straight line interpolation between data points.
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Because the path of the contact front is assumed to be linear in the PAVA method, the best-fit axis of the transect orientation through sampled individuals was estimated using a one-dimensional cline fitting with a straight centerline.
In the case of the conventional CT, the interior is estimated using a mathematical inverse transform based on an assumption that paths are straight and parallel.
1/S' was estimated using BlastPhen.
Nucleotide diversity was estimated using DnaSp 4.10 [38].
Confidence intervals were estimated using normal approximation.
RNA concentration was estimated using nanodrop spectrophotometer.
Divergence times were estimated using Multidivtime [52] [54].
Protein concentration was estimated using Coomassie Plus Protein Reagent.
Effects were estimated using conditional logistic regression.
Statistical power was estimated using 1000 simulations.
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