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If the CRF is available, the camera noise parameters α j, β ij, σ o, j 2 can be estimated directly using a (robust) linear regression on the the inversely compensated pixel intensities γ−1 z ij ), relying on (17).
Despite their complexity, such population surveys are increasingly feasible because HIV incidence can be estimated directly using serologic assays that distinguish recent from established HIV infections [ 14– 16].
"In cohort studies on acute disease without induction period and a short time of follow up, like outbreaks, the risk of disease can be estimated directly using the cumulative incidence given a fixed cohort with fixed period of follow up and a low fraction of drop-outs" [ 37].
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The nip angles were estimated directly using experimental pressure profile data of each run.
The required power input for the heaters is estimated directly using inverse design so that specified thermal conditions across the silicon wafer are achieved at steady state.
The MW was estimated directly using the P r) distribution function from the web server (http://www.if.sc.usp.br/~saxs/saxsmow.html) (Fischer et al., 2010).
Disease penetrance was estimated directly, using the ratio of unilaterally to bilaterally deaf dogs, and segregation analysis was performed using Mendel.
The attributable risk of the short-term exposure was estimated directly using the distribution of exposure in the cases [ 18].
In the second approach, genomic breeding values are estimated directly using an equivalent model with a genomic relationship matrix.
MLR is similar to the full information maximum likelihood (FIML) method, in which missing data are not imputed, but parameters and standard errors are estimated directly using all the observed data [ 50].
Regarding the Markov model, the transition probabilities are estimated directly using the estimates P ^ 02 (t ) and P ^ 06 (t ) based on the estimated transition probability matrix, whereas the expression proposed in this paper suggests estimating the probabilities of interest in an indirect manner using the Aalen-Johansen estimates of the cumulative incidences.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com