Sentence examples for be established with confidence from inspiring English sources

Unless full PK/PD relationships can be determined, the drug target candidate profile for first in class targets cannot be established with confidence; consequently, chemistry strategy cannot be implemented without risks.

However, the phylogenetic relationships among the tested isolates determined from different methods of analysis are not always consistent and could not be established with confidence.

Because of the cross-sectional nature of the study, the temporality of certain associations cannot be established with confidence.

Specifically, an enhancing stalk is seen in many polyps, allowing the diagnosis to be established with confidence (Fig. 7).

Few relevant differences could be established with confidence in unigenes potentially specific for roots, probably owing to their significantly smaller number, likely determined by the considerably smaller number of reads obtained from this tissue.

Moving forward, we encourage the evaluation of the relative success of barcoding in an explicitly phylogenetic context, where the relative relatedness of the species being sampled can be established with confidence.

Of the examined notes, there were 55 patients for which a clinical diagnosis could be established with high confidence, based on the Queen Square Brain Bank criteria for the diagnosis of PD.

The four populations found by Structurama fit perfectly with the mitochondrial and genome trees and thus group assignment could be established with high confidence for all the samples.

In addition, adequate treatment was felt to be established with more confidence and in shorter time as compared to cases without sputum data.

We find that RBSets leads to good performance in identifying additional interactions starting from a small evidence set of interacting proteins, for which an underlying biological logic in terms of functional processes and signaling pathways can be established with some confidence.

Because of data limitations (both temporal: number of years, and spatial: number of WIM sites), more in-depth seasonal variations in truck traffic could not be established with a high confidence level.