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It remains to be established whether these differences reflect the different experimental interventions used, differences in cells examined, or differential interactions and physiologic outputs that occur during adipogenesis versus fully differentiated adipocytes.
It remains to be established whether these changes in intracellular volume also occur in cells growing in tissues, and if so, what triggers them, what mechanisms are responsible for their regulation, and what, if any, is the importance to the physiology of the cell.
It remains to be established whether these epitopes are relevant from a pathophysiological point of view.
It remains to be established whether these cells have the properties of beta cells.
It remains to be established whether these different regulatory routes are stimulus- and/or tissue-specific.
It remains to be established whether these low affinity interactions play any functional role in vivo.
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It remains to be established whether the orthologues of these genes could be associated with pyrethroid resistance in A. funestus.
Therefore, it still has to be established whether the autocrine production of these growth factors represents an adaptation or a true bypass of the AR signaling pathway.
First, if the new model, like Durgin's, is to adjust influence-sphere size on the basis of summary statistics, then it needs to be established whether the perceptual system computes these summary statistics across items defined in second-order motion, and whether it uses these statistics to adjust influence spheres.
Nutrition has been found to be associated with cognitive impairment, but it has not been established whether these associations are present solely in later life or whether they are present in younger age as well.
However, it has not been established whether these injuries were genuinely 'occult' or whether they had been missed by the doctor or midwife at delivery.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com