For medical treatment of GH excess (acromegaly), somatostatin analogs, dopamine agonists and a GH antagonist (GHA) are established in routine clinical practice (Katznelson et al., 2011).
If a dark adaption step can be established in a routine measurement the change of pigment composition within a species over time has to be considered.
Students in the present study were not regularly meeting patients on a one-to-one basis, and may have needed more opportunities to practise their skills for improvements to be established in their routine behaviour.
In acute headache with its high burden of disease [44], no biomarker has been established in clinical routine to improve discrimination between serious secondary and benign headache forms, even though fast and early identification of serious secondary headaches at the ED is crucial and has remained an unmet clinical need [2].
To compare biomechanical results, it seems to be mandatory that fracture morphology is rated by using classification systems, which are established in clinical routine.
Nevertheless, the underlying mechanisms in wound healing disturbance are not completely understood and so far none of the potential biomarkers for dysregulated wound healing was established in clinical routine diagnostics.
The assay design included ready-to-use recombinant proteins as calibrators, run-validation control samples, and internal quality controls samples (for which target value and acceptance criteria were established in the routine setting of AD biomarker quantification).
However, if this novel method is established in the clinical routine, Mendeliome sequencing is feasible within 72 h (Illumina Truesight One Manual 15046433, 2013).
Mostly due to lacking specificity and sensitivity of these markers, none of these tests are established in the clinical routine and post-transplant care of the patients [ 4].
The protocol was established in 2006 as clinical routine in our department.
