Sentence examples for be established in large from inspiring English sources

This was a small study; thus, the clinical value of this test can only be established in large trials.

The challenge of optimizing culture conditions for maintenance of pluripotency is the primary reason stable ESC lines have yet to be established in large animals [33], [34].

GHR strategic planning requires decision makers and managers to find out what truly is important to the communities they are trying to help, which must be established in large part by engaging partners in vulnerable communities of concern.

This approach also needs to be established in larger populations with a focus on specific tumor types.

Whether alterations in both these genes may be able to confer a more aggressive phenotype remains to be established in larger series.

Public brothels were established in large cities throughout Europe.

This framework was established in large part by the justice movement initiated by former World War II "comfort women" in Korea and that has been joined by other surviving victims throughout Asia.

Formally designated in 1996, the Monument was established in large part to facilitate preservation and study of its diverse natural resources, both living and fossil.

Clinicians should use newer quinolones cautiously until their safety has been established in large patient populations.

Finally, broad applicability, acceptability and a complete safety profile is established in large single-group observational trials.

The anti-fracture efficacy has been established in large outcome trials of 3 4 years' duration, but long-term fracture data in major study populations are missing.