Sentence examples for be established by randomized from inspiring English sources
Finally, while the improvements of clinical endpoints are encouraging, the prognostic value of carotid baroreceptor stimulation in HF needs to be established by randomized trials and hard endpoints.
Some have suggested that the relation between dietary fat and breast cancer can only be established by randomized trials of fat reduction.
The combination of 5-fluorouracil and bevacizumab was established by two randomized phase II trials, demonstrating prolonged progression free (PFS) and overall survival (OS) and higher objective response rates (ORR) for the addition of bevacizumab to a bolus regimen of 5-fluorouracil and leucovorin (5FU/LV) [ 10, 11].
Significance of protein assignment to clusters was established by base composition-preserved randomized pairwise global alignments using the method of Needleman and Wunsch [ 26, 57].
Tranarterial chemoembolization (TACE) has been established by a meta-analysis of randomized controlled trials as the standard of care for nonsurgical patients with large or multinodular noninvasive hepatocellular carcinoma (HCC) isolated to the liver and with preserved liver function.
Transarterial chemoembolization (TACE) has been established by a meta-analysis of randomized controlled trials as the standard of care for nonsurgical patients presenting with large or multinodular noninvasive tumor isolated to the liver and preserved liver function [ 6].
In addition, the determination of the statistical significance of this relation was established by the use of phase-randomized surrogates.
The superiority of plerixafor in combination with G-CSF over G-CSF alone was established by several phase II [ 85– 89] and two phase III multicenter randomized double-blinded placebo controlled studies [ 84, 90].
