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Incorporating these findings into the design of future clinical trials and as companion diagnostics to routine pathology will be essential in evaluating their significance in personalized approaches for patients with these deadly diseases.
Well-defined genetically engineered mouse models that represent the heterogeneity and complexity of tumor etiology, such as TP53 null tumor models, will be essential in evaluating immunological effects on tumor development and therapeutic response [ 34].
These types of integrative studies, where genetic differentiation, ecological opportunities, and physiological limits are explicitly considered, will be essential in evaluating the capacity for populations to adapt to global warming.
There are only limited amount of data on the interrelationships between different inflammatory cell types (Nagtegaal et al, 2001) and inflammatory cell reaction grading methods (Roxburgh et al, 2009b; Richards et al, 2012a) in CRC, which would be essential in evaluating their relative significance.
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Energy, water and carbon footprinting across the entire supply chain are essential in evaluating business risk.
A careful medication history is essential in evaluating GERD patients, as a simple medication change may greatly reduce symptoms.
This undermines the transport properties of concrete, which is essential in evaluating concrete durability.
Hence, assessment of the outcomes of patients is essential in evaluating the success of PBM programmes.
Understanding the diverse etiologies of female urethral stricture and loss is essential in evaluating and diagnosing patients.
Accurate monitoring of an introduced, mass-released microbial control agent is essential in evaluating its persistence and in designing application strategies for insect pest control.
Characterizing properties of the rock matrix that control retention and release of chlorinated solvents is essential in evaluating the extent of contamination and the application of remediation technologies in fractured rock.
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