Sentence examples for be essential for triggering from inspiring English sources

Therefore, the NMDAR is a major hub for the regulation of PSD structure and composition and its activation appears to be essential for triggering disassembly of the PSD; however, our study demonstrates that divergent downstream signalling pathways regulate the demise of each PSD component.

We found that Nek1 levels decreased after serum stimulation, suggesting that the degradation of Nek1 could be essential for triggering the destabilization of the primary cilium.

All these data suggest that the relative movement, i.e. the change in distance between the two linker regions, is essential for triggering the activation of the 7-TM domain, and support the importance of the linker-ECL2 interaction.

We have previously shown that this region is essential for triggering bacterial invasion of endothelial cells [17], [30].

Collectively; our data suggest that the lipid motif of the lipoprotein antigen is essential for triggering TLR2 signaling and effective stimulation of APCs.

Upon viral infection, IPS-1 associates with RIG-I or MDA5 at the mitochondrial outer membrane via the CARD-CARD interaction, which is essential for triggering downstream signaling that activates NF-κB and IRF.

Gonadal secretions are essential for triggering and maintaining sexual dimorphisms.

During intrinsic apoptosis, MOMP is essential for triggering the apoptosis execution phase.

In mammals, antigen processing and presentation are essential for triggering the downstream cellular and/or humoral immune responses [ 41].

Taken together, these results demonstrate that the phosphodegron identified in hBora is functional and that Plk1 binding is essential for triggering the β-TrCP-mediated degradation of hBora.

One mechanism by which VRK2 might regulate apoptosis is by regulating, directly or indirectly, the expression of BAX, which is essential for triggering apoptosis.