Sentence examples for be essential for stem from inspiring English sources

More recently, a p53-binding protein, named nucleostemin (NS) abundantly expressed in stem and cancer cells but silenced in differentiated cells, has been shown to be essential for stem and cancer cell proliferation and survival (Tsai and McKay, 2002).

The fact that CXCR4 is present in normal mammary stem cells suggests that this molecule may be essential for stem cells that appear to be progenitors of breast carcinoma [ 26].

Of note, the Hh signaling is known to be essential for stem cell self-renewal, organ homeostasis, and wound repair in many tissues, and constitutively activated in many types of cancer.

However it is presently unclear to what extent telomere length maintenance via TERT is essential for stem cell activation.

The recent observation that adhesion molecules are not only important determinants for the molecular, but also mechanically guided lineage selection and differentiation of stem cells [55] adds to the concept that adhesion molecules are essential for stem cell biology.

Non-coding RNAs (ncRNAs) are a class of molecular species that, for example, play regulatory roles, have been implicated in human diseases, and are essential for stem cells [1], [2], [3], [4], [5].

In addition, recent evidences have shown that NHEJ repair activity, among others DNA repair pathways, is essential for stem cell maintenance, and a decline in DNA repair function with age is observed [54].

The stem cell niche is essential for stem cell functions.

NS is essential for stem- and cancer-cell proliferation [ 4].

The AtWOX5 protein is essential for stem cell maintenance via a negative feedback signal provided by CLE40 [ 11].

These observations demonstrate that Ddb1 is essential for stem cell self-renewal and differentiation in both HSPC and ESC.