Sentence examples for be essential for replication from inspiring English sources

IRs flanking the origin of DNA replication with the potential of forming single-stranded stem-loop cruciform structures have been reported to be essential for replication of the circular genomes of many prokaryotic and eukaryotic systems [5].

The ATPase activity of the geminivirus Rep protein was proven to be essential for replication [ 16].

Furthermore, RAD51 was recently shown to be essential for replication fork reversal and restart upon different types of replication stress conditions (Zellweger et al, 2015).

Although pretreatment of the promastigotes with lactacystin did not inhibit cell invasion, proteasomal function seems to be essential for replication and intracellular survival of amastigotes in the host cell [ 58].

In more detail, palindromic motifs (and in general inverted repeats) have the potential to form single-stranded stem-loop cruciform structures which have been reported to be essential for replication of circular genomes in many prokaryotic and eukaryotic systems [ 72].

Auto-processing by the virally encoded NS2-3 protease is responsible for cleavage at the NS2/NS3 junction; this activity has been demonstrated to be essential for replication of full-length virus and subgenomic replicons that span the NS2-NS5B region (Fig. 1A) [10,11].

The ribonucleoprotein (RNP) complex of influenza virus consists of four subunits PB2, PB1, PA, and NP, which are essential for replication.

Picornaviruses have a 22 24 amino acid peptide, VPg, bound covalently at the 5′ end of their RNA, that is essential for replication.

These results show that the NUMT component of ARS1635 and ARS1215, and in particular the ACS motif, is essential for replication activity since its disruption is associated with the loss of replication activity of the entire region.

Human immunodeficiency virus type I reverse transcriptase (HIV-1 RT) is essential for replication of the viral genomic RNA into a double-stranded DNA intermediate that is subsequently integrated into the host genome.

In infected cells, Tat transactivates virus gene transcription and is essential for replication.