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This atypical structure has been shown to be essential for normal fertility and embryo development15,17.
Moreover, the presence of low-abundance bacterial strains may be essential for normal contractile activity.
Payne, V. A. et al. The human lipodystrophy gene BSCL2/seipin may be essential for normal adipocyte differentiation.
In the model DD, ∼385 genes have been recognized by gene disruption to be essential for normal progression through multicellular development.
FGFRL1 is known to be essential for normal skeletal and cardiovascular development in humans and mice25,26,27, and the FGF pathway regulates somite size51.
The G3 region appears to be essential for normal trafficking of the aggrecan within the chondrocyte and for its secretion into the extracellular matrix (ECM) (Zheng et al. [1998]).
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Synaptic protection is essential for normal brain development.
Enteric glial cells are essential for normal gastrointestinal function.
Skin integrity is essential for normal physiological function.
The BMM is essential for normal hematopoiesis, but also for leukemogenesis [26, 49, 50].
Campbell, C. E. et al. The transcription factor Nfix is essential for normal brain development.
More suggestions(16)
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