Sentence examples for be essential for interaction from inspiring English sources
While DevRC interaction with DNA oligonucleotides containing two consensus binding sequences was shown by crystal structure analysis [18], phosphorylation of intact DevR at Asp54 was found to be essential for interaction with DNA [20].
While the conserved N-terminal region is recognised to be essential for interaction with ferroportin [ 18], the role of the C-terminal side is not well defined.
Any of these apparently small structural differences may be essential for interaction of Dil with its intracellularly or extracellularly accessible binding sites.
Our recent resolution of the crystal structure of the BtpA TIR domain reveals that the motif positions a glycine residue that has previously been shown to be essential for interaction of BtpA with microtubules.
However, FOXP3 exon 2, which encodes for a portion of the FOXP3 repressor domain, has been specifically shown to be essential for interaction with and repression of retinoic acid related orphan receptors α and γt (RORα, RORγt) [ 34, 35].
Deletion of this region in fly shows loss of PC function [ 40], and has been shown to be essential for interaction of PC homologues CBX2 and CBX8 with RING1A which is a homologue of fly dRING and a component of PRC1 [ 43, 44].
The correct conformation of Clp1 induced by ATP binding may be essential for interactions with other protein factors in the machinery, including Ssu72, Ysh1, Pta1, and Rna14.
Using domain dissection and cross-linking mass spectrometry, we identified a unique region of Pih1p that is essential for interaction with Rvb1p/Rvb2p.
Typically, tubulin inhibitors that bind to the colchicine binding site bear the trimethoxyphenyl (TMP) moiety which is essential for interaction with tubulin.
