Sentence examples for be essential for embryonic from inspiring English sources
The methyl-CpG binding domain protein MBD3 has been shown to be essential for embryonic development and differentiation, and to act by suppressing gene expression through the recruitment of co-repressor complexes.
Since some of these genes have been revealed to be essential for embryonic development, we propose that the zebrafish, a vertebrate model organism possessing many advantages for developmental studies, can be utilized to study the biological functions of these genes and the related epigenetic mechanisms during early development.
Thymine DNA glycosylase (TDG), a member of the uracil DNA glycosylase (UDG) superfamily of DNA repair enzymes, has been shown to be essential for embryonic development [ 13].
Moreover, although PTEN does not exhibit a specific intracellular localization, it binds to proteins localized to tight junctions in epithelia, and appears to be essential for embryonic development in mice.
In Atlantic halibut embryos, tpm3 expression started after somite formation (10SS) and was highly expressed at HT. Isoforms of tpm3 have been previously found to be essential for embryonic development in mice, but the underlying mechanism is unknown [ 49].
Of all the CKIs, only p57Kip2 has been shown to be essential for embryonic development, as p57Kip2 null mice display significant congenital defects such as cleft palate, omphalocele and short limbs [ 11- 13].
Studies on a null mutation in mice previously revealed that Nup133 is essential for embryonic development but not for mouse embryonic stem cell (mESC) proliferation.
Retinoic acids are essential for embryonic development, tissue organization, and homeostasis and act via retinoic acid receptors (RARs) that form heterodimers with retinoid X receptors (RXRs).
Cyclopamine, it turns out, blocks the function of a gene called Sonic hedgehog that is essential for embryonic development but also plays a lead role in causing deadly cancers of the pancreas, skin, prostate and esophagus.
Hdac3 is essential for embryonic development [11], [12].
