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Further knowledge about this issue may contribute to understanding the cause and complications of migraine and may be essential for development of treatment approaches.
The structural difference between two splice isoforms markedly affects the specificity of ligand receptor binding [7], [8], [9], and exon switching is shown to be essential for development in the mouse [10], [11].
From analysis of knockout mice, both IRE1α and XBP1 have been shown to be essential for development and that XBP1 is necessary for the secretory machinery of exocrine glands, plasma cell differentiation, and hepatic lipogenesis.
YY1 is known to be essential for development because knockout of YY1 in mice results in peri-implantation lethality [ 48].
About 3000 5000 of the 20,000 genes in C. elegans are estimated to be essential for development and survival.
However, dopaminergic neurotransmission appears to be essential for development of conditioned preference for ethanol-associated cues [ 54].
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Moreover, financial market liberalisation may undermine countries' ability to learn another set of skills that are essential for development: how to allocate resources and manage risk.
A working item bank is essential for development of a CAT platform.
Hence, it is essential for development of such reservoirs to study the influence of stress to produce on commercial rates.
ATAD3 is absent in yeast and protozoan and present in all pluricellular eucaryotes where its expression is essential for development.
Designing systematic innovation policies are essential for development and commercialization of new technologies in this important futuristic research area.
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