Sentence examples for be essential for binding from inspiring English sources

The E37A mutation increases the affinity of TetR for tetO variants and seems to be essential for binding to modified operator sequences.

Jos_W87K mutates an exposed hydrophobic tryptophan found to be essential for binding both Ub and the Ubl of hHR23B to site 2 [18].

Four conserved amino acids identified in this study are proposed to be essential for binding with the substrate and they form two distinguishable sequence motifs.

The cysteine at position 706 of Rb was reported to be essential for binding to LxCxE motif-containing proteins such as the SV40 large T antigen [18], [19], possibly due to the destabilization of the Rb C-terminus [19].

On the other hand, the sequences do not conserve residues in the TPR domain known to be essential for binding to Rac [ 10].

Residing within this ring is a highly conserved glutamate residue, which has been shown for mersacidin to be essential for binding to lipid II (33).

Mutants 1 and 2, in which the first four nucleotides (TGAC) and the last four nucleotides (CTCA) were altered, respectively, did not bind to JunB, demonstrating that these AP1 sequence (TGAG/CTCA) are essential for binding to JunB.

The HIV envelope protein (Env) is essential for binding to a human lymphocyte or T cell.

According to Istvan et al.[17], this part mimics the original binding ligand and consequently is essential for binding.

All four hydroxyl groups of RosA were essential for binding with the p56lck SH2 domain and T-cell inhibitory activity.

Molecular modeling studies concluded that recognition with key amino acid Arg38 and Lys31 are essential for binding and biological activities.