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Chemical and pharmacological modulation of ER stress was shown to be essential for bacterial elimination.
Therefore, high energy-requiring processes are likely to be essential for bacterial survival in selected environments.
Furthermore, PrtV was found to be essential for bacterial killing of the nematode Caenorhabditis elegans, a phenomenon associated with colonization of the C. elegans intestine [10].
Strikingly, although not required for intracellular survival in cell culture models, TrkH appeared to be essential for bacterial virulence in the mouse.
The accumulation of truncated proteins or mRNAs may be lethal or tmRNA-dependent tagging of a specific protein could be essential for bacterial survival.
The bacterial stress protein HtrA (high-temperature requirement A) has been found to be induced in intramacrophagic AIEC bacteria and to be essential for bacterial intracellular multiplication [21].
Similar(44)
Fatty acid biosynthesis is essential for bacterial survival.
The bacteria-specific membrane component lipid II is essential for bacterial cell wall synthesis.
The posttranslational deformylation of N-formyl-Met-polypeptides by the metalloenzyme, peptide defomylase, is essential for bacterial growth.
This protein is essential for bacterial growth, making it an attractive target for the design of new antibiotics.
The mechanism of action involve inhibition of an enzyme topoisomerase II (DNA gyrase), which is essential for bacterial DNA replication [22].
More suggestions(15)
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