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Exact(11)
Since Sec residue is contained in the active site of GPx, Sec is thought to be essential for activity [24].
Several characteristic features were observed to be essential for activity such as the morpholine group and the phenylazo group, in addition the electron-withdrawing groups favor the activity than the electron-donating ones.
This domain includes a histidine found to be essential for activity in the non-specific endonuclease from Serratia marcecens [24].
The assembly of the plasmodial PLP-synthesis machinery follows a hierarchically defined course, which seems to be essential for activity [19].
The strong regulation of Pdu protein expression by Hfq suggests the pdu operon to be a potential target of sRNA regulation and that correct coordinate expression may be essential for activity.
However, site-directed mutagenesis of CV 3C protease has suggested that the third acidic amino acid may not be essential for activity (19).
Similar(49)
Here, we also show that the nuclease domain of G2P is not active in isolation, suggesting that interactions with the ATPase domain are essential for activity.
The formation of stable Cu2Cl(OH)3 was essential for activity and stability of the catalyst.
It was noted that carbamate and N,O-aminal groups were essential for activity.
The D614 carboxylate appears to ion pair with the amino group of homocysteine and is essential for activity.
We conclude that these aromatic residues are essential for activity but are not significantly involved in binding of the substrate or cofactor.
More suggestions(17)
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