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In fact, genome-scale networks can detect enzymes that are likely to be essential and selective.
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He also stresses that recruiting for aptitude is essential, and forcing up the numbers through selective recruitment would be counterproductive.
Autophagy adaptor proteins, including SQSTM1 and NBR1, have been revealed to be essential in mediating selective autophagy.
Nevertheless, it will be essential to develop highly selective molecules that enable the targeting of specific sirtuins, as their effects may, under some circumstances, overlap due to cross talk between different family members.
Acquiring resistance to bacitracin and neomycin may be essential for survival under the selective pressure of TAOs.
In the skin, VR1 is essential to selective modalities of pain sensation and to tissue injury-induced thermal hyperalgesia (Caterina et al. 2000).
Understanding the role and influence of each specific heterodimer in mammary tumorigenesis might be essential to develop a more selective therapeutic approach.
Although these proteins do not appear to be essential, they presumably confer a selective advantage to their carriers, as becomes apparent in vitro when mutant cells are challenged with antibiotic, acidic, or oxidative stress [ 4, 5].
To achieve this goal, inner nanopore wall functionalization is essential to selective DNA translocation [12].
These results reveal that activation of the NFκB pathway is essential for selective expansion of the B1a cells in the peritoneal cavity of the Siglecg−/− mice.
A diverse range of isatin-β-thiosemicarbazones were initially synthesized to identify general regions of the molecule that were essential for selective activity.
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