Hence, in a group of people affected by a disease, the SNPs causing or associated with the disease will be enriched in frequency compared with the corresponding frequencies in a group of unaffected individuals.
In addition to CNP934 on chromosome 6, four other CNVs were enriched in patients with T1D and unaffected twins at high risk to develop islet-specific autoimmunity and diabetes.
Most CMD discharges are enriched in total rare earth elements relative to concentrations expected in unaffected surface or ground waters, generally by 1 4 orders of magnitude.
However, by studying unaffected relatives from NPC multiplex families, the population is enriched in terms of EBV IgA antibody positivity, which occurs at much lower frequencies in the general population (Pickard et al, 2004).
Postpancreatitis necrotic collections were enriched in UFAs.
Each is enriching in its own way.
As a visitor to the fair since 1972, I am convinced that the life of the city is enriched by this unaffected expression of a rural Brazilian culture that is rapidly vanishing.
In fact, if a gene variant causes depression, T2D, and MetS, it would be difficult to identify it by association unless the case group is enriched of those phenotypes and the control group is unaffected by all those phenotypes.
Our analyses highlighted seven co-expressed modules that were enriched with genes that could discriminate pSS patients from unaffected individuals using parotid gland tissue, a prime target in Sjögren's syndrome pathogenesis.
We see that clusters which are enriched for differential H3K4me3 patterns systematically have a decrease in Pol II, while clusters which are unaffected by the Cfp1 deletion seem to have rather stable Pol II levels.
