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The LIG_MAPK_2 pattern was not considered in this analysis because it was not found to be enriched in human ERK1/2 substrates, and it was not expressed by the HIV proteome (data not shown).
Additionally, intravenous administration of lentivirus causes infection of tissues known to be enriched in human immune cells, including the spleen and bone marrow[5], or which function as an endogenous source of IL-7, such as the liver[22].
Consistent with previous findings, we observed the pyrimidine-purine (YR) step to be enriched in human TSSs (Fig. S1).
In addition, a 13-mer motif contained in the binding sites of PRDM9 is found to be enriched in human hotspots.
PRDM9 binds to DNA and its binding site contains a 13-mer motif previously found to be enriched in human hotspots [ 6].
Several of the most abundant microRNAs in our dataset were previously shown to be enriched in human erythrocytes, thus validating our findings.
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Given the large number of compounds against biogenic amine receptors that increased nematode lifespan in the present studies, it is intriguing that an allelic variant of one such receptor, dopamine DRD4, is reported to be enriched in humans over the age of 90 (Grady et al., 2013).
Mei, H. E. et al. A unique population of IgG-expressing plasma cells lacking CD19 is enriched in human bone marrow.
We conclude that UFAs are enriched in human necrotic collections and acute UFA generation via lipolysis worsens pancreatic necrosis, systemic inflammation, and injury associated with severe AP.
Since the soil in certain environments – graveyards, for example – is enriched in human remains but does not accumulate these substances, it presumably harbours microbes that degrade them.
Previous studies have shown that synteny breakpoints between the mouse and the human genomes are enriched in human segmental duplications, suggesting a causative connection between such structures and evolutionary rearrangements.
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