Sentence examples for be enriched for true from inspiring English sources

Exact(5)

However this current calculation will already be enriched for "true" human CpG beacons that can facilitate unique species-specific epigenomic variation.

Conversely, if the phenotype were polygenic, but the causal variants were in number of hundreds and showed strong population differentiation, the extremes of the empirical distribution of our conditional informativeness (CI n ) statistic would be enriched for true causal variants.

The fact that the joint distribution of F ST and H BP generated under the HIM much better fits the observed distribution than that obtained under the FIM suggests that the HIM captures key aspects of human demography and that the identified outlier loci are more likely to be enriched for true signal of selection.

Therefore, if the African Pygmy phenotype is largely determined by less than a few hundred of SNPs that show large population genetic differentiation, we expect that the extremes of the CI n distributions will be enriched for true loci involved in the Pygmy stature.

We also compared the different scoring methods based on overlap with two independent sets of interactions that should be enriched for true positives: the Prolinks predictions and a recent set of binary interaction data derived from large-scale protein complementation assays (PCA) (Tarassov et al., 2008).

Similar(55)

Of validated deletions within this set, calls made by multiple methods were enriched for true positives much more than false positives.

As noted, the results do support the possibility that the selected markers are enriched for true associations to the humoral immune response to influenza vaccine.

The quantile-quantile plot from the association tests performed on these SNPs shows marked deviation from the empirical null distribution for QTL associations, supporting the idea that these loci are enriched for true genetic associations.

We show that when multiple correlated SNPs are present in a hit region that has been identified by standard single-locus regression, LLARRMA produces a reprioritization that is enriched for true signals.

T cells with the phenotype CD4+CD45RA+CD31+ have significantly higher TREC content per cell than unselected CD4+ T cells, 16 confirming that this subset is enriched for true thymic emigrants.

We apply LLARRMA to simulations based on case-control genome-wide association studies data, and find that when there are several causal loci and strong LD, LLARRMA identifies a set of candidates that is enriched for true signals relative to single locus analysis and to the recently proposed method of Stability Selection.

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