Sentence examples for be enriched for interactions from inspiring English sources
We therefore hypothesized, based on the notion that our study sample was markedly underpowered, that the 0.5% most significant interactions would be enriched for interactions involved in MDD-susceptibility.
Our results show that many of the genes/proteins involved in the GR pathway are enriched for interactions of two or more of the metals.
We therefore hypothesize that the most significant interactions are enriched for interactions implicated in MDD-susceptibility from these candidate genes and thus provides indicative information for genetic risk for MDD (Table 1A-D).
The set was found to be enriched for protein-protein interactions compared with a genome background (P = 0.0001).
If redundancy explains the presence of nonessential genes within essential protein complexes, then essential complexes should be enriched for negative genetic interactions.
We found that the number of interactions between pairs of proteins that participate in the same KEGG pathway was much larger in HCS than LCS, and that LCS had more interactions belonging to the same KEGG pathways than RPS (Fig. 3C) Next, we compared the scored Drosophila PPI with two independent datasets that should be enriched for biologically relevant interactions (Fig. 4).
We also compared the different scoring methods based on overlap with two independent sets of interactions that should be enriched for true positives: the Prolinks predictions and a recent set of binary interaction data derived from large-scale protein complementation assays (PCA) (Tarassov et al., 2008).
Our method is trained to recognize these regions based on the presence of coding, conserved non-coding elements (assumed to be enriched for regulatory regions) and their putative interactions.
SNPs involved in interactions appear to be enriched for promoter markers.
We hypothesized that the interaction partners of the baits would be enriched for cell cycle regulators relative to random proteins.
Cis-cis interactions are enriched for physical interactions in all tissues (Table 2).
