We have recently reported a novel strategy for the design of non-natural allosteric-inhibition sites in PTPs, in which a tricysteine moiety is engineered within the PTP catalytic domain at a conserved location outside of the active site.
The transfer construct was engineered within the multiple cloning site (MCS) between the two I-CeuI homing endonuclease restriction sites of plasmid pCeu2.
Hence, this study demonstrates how collagen fiber structures can be engineered within all regions of a multiphase tissue scaffold by exploiting knowledge of collagen assembly, and presents an approach to engineer local collagen structure that complements methods such as flow alignment and electrospinning.
Scott Browning, the acting director of Souls Grown Deep — a nonprofit foundation, started by Arnett, that owns most of the collection — says that the pieces are "engineered within an inch of their lives," adding, "We joke that you could balance a Dial assemblage on the tip of a pencil".
Formula One cars are engineered within an inch of their lives, and even a nearly imperceptible movement imparted upon the wheel can send you crashing into a wall.
A single point mutation was engineered within Annexin A2-expressing vector, with resulting vectors called pEXS-Annexin A2-K302A and pEXS-CG-Annexin A2-K302A.
If hospitals were efficiently operated, if doctors' time were conserved, if economical concentration of patients and laboratories were permitted, in other words, if health could be engineered to be within the purchasing range of the masses, doctors would be better paid and we would save billions in wasted life and suffering.
Interlocked structures can be engineered to bind specific guests within the topologically constrained three-dimensional cavities created during their template-driven syntheses.
The lack of observed deactivation may indicate the potential that highly efficient (with respect to utilization of available electrons) dechlorination reactions can be engineered to occur within nonaqueous liquids.
