Sentence examples for be engineered to knockdown from inspiring English sources

Importantly, these artificial miRNA shuttles can be engineered to knockdown any gene of interest [ 9, 25, 26, 28, 29].

First, NSCs can be engineered to produce different genes.

Recently, a mouse strain was genetically engineered to knockdown the expression of Cox-2 [32].

The role of resistin in insulin resistance was also investigated in mice, engineered to knockdown or overexpress resistin.

It is engineered "to lock in hydration".

"The process is engineered to avoid that," he says.

This can be engineered.

Here, we used quantitative phosphoproteomics to generate a global picture of phosphorylation events regulated by PPP1R12A in a L6 skeletal muscle cell line, which were engineered for inducible PPP1R12A knockdown.

For knockdown-rescue experiments, cells were transfected simultaneously with siSTAT5b SMARTpool duplex #3 and HA-tagged wild-type-, Y699F-, dominant-negative-, R618K-STAT5btobeengimmuned to be immune to knockdown by introduction of four silent point mutations in the siRNA target sequence.

Rescue of ERBB4 expression in 1410 or 1411 kd cells using an ERBB4 construct engineered to be resistant to knockdown through silent mutations in the ERBB4 shRNA targeting region restored ERBB4 expression and Akt activation in ERBB4 kd cells (Supporting Information Fig S2C), validating the specificity of these shRNAs.

For Sp1 protein knockdown, pSuper-Sp1 plasmid was engineered as described [ 25], with the Sp1 target sequence: 5′-CCTGCAGCAGAATTGAGTC-3′ for mouse, and 5′-GAATCGCACA GTCTCTGGT-3′ for human.