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Transgenic Caenorhabditis elegans animals can be engineered to express high levels of the human beta amyloid peptide (Abeta).
Yeast cells encode a single beta-tubulin gene and can be engineered to express just one of two alpha isotypes.
The Rose laboratory has developed vaccine platforms based on recombinant viruses that can be engineered to express high levels of foreign antigens.
GFP was a common tool in cellular research; cells of a certain type could be engineered to express the protein and thus would be more easily visible.
Mouse cells can be engineered to express the human orthologs of the entry molecules CD81 and occludin to allow entry of HCV.
These results also indicate that NDV can be engineered to express foreign protein stably and can be manipulated in the future for use as a vaccine vector.
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E6.1 Jurkat cells, which lack endogenous CD44 expression, were engineered to express CD44.
The human glioblastoma cell line, U87MG, which had undetectable hDkk-1 expression, was engineered to express moderate levels of the hDkk protein by stable transfection.
To gain insight into TGFβ signalling in vivo, MTln3E cells were engineered to express either GFPSmad2 or a Smad3 responsive promoter driving the expression of ECFP (CAGA::ECFP).
Isogenic p53-null H1299 cells were engineered to express the p21 protein by two different procedures.
Normal and cancer cells were engineered to express the KRAS(G48A) mutation.
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